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Studies indicate berberines therapeutic potential for ameliorating secondary brain damage following TBI

Shokuhin Eiseigaku Zasshi 58 , 268274 (2017)

In the technical scheme, in the step 3, the prepared solution is dissolved and clarified by stirring, the injection water is added to the full amount, and the pH value is adjusted to 6.9 by 10% sodium hydroxide solution

K., Kato, Y., Takagi, J

REST acts by suppressing GCLM expression, leading to decreased GCL activity and limited GSH synthesis that indicates higher sensitivity to ferroptosis