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Published clinical studies have used topical GHK-Cu at concentrations of 14%

however, it may be indicative of a functional change in a different sensory modality independent of Von Frey testing (i.e., mechanoreception, proprioception, or thermosensation)

Chen P, Zhong Y, Chen K, et al (2020) The impact of discharge reduction activities on the occurrence of contaminants of emerging concern in surface water from the Pearl River

doi: 10.1016/j.bpobgyn.2007.07.009 131 KostrounKEGoldrickKMondshineJNRobinsonRDMankusEReddySet al

TGF- ligands bind and activate a heteromeric complex of type I and type II transmembrane serine/threonine kinase receptors