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Briefly, subcellular glutathione can be bound in situ or in vivo to glutathione-specific antibodies (total glutathione = sum of GSH and GSSG), redox-sensitive dyes (monobromobimane [mbrB] or monochlorobimane [mchlB]

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It does this by activating a master transcription factor, NRF2

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Discussion We provide, for the first time, direct evidence that only 38 days of extra oral glucose intakes four times a day can induce prediabetes