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In fact, periodic breaks may enhance subsequent responsiveness by allowing receptor upregulation during the rest period

In a similar way, acrolein appears to stimulate oxidative stress damage, producing high levels of ceramide, which is accountable for the incrementation of cytosolic Ca 2+ concentration and, consequently, the eryptosis levels [254]

Curcumin modulates various signaling pathways, including the Nrf2 pathway, which enhances the expression of antioxidant proteins and enzymes [150]

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in 2010, and we took this review into account when revising the table that appeared in previous editions