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A., Aisen, A

Where microtubules are destroyed, and tau oligomers (tauO) are pathological, p53 cannot enter the nucleus

Although PCBP depletion leads to loss of c-aconitase activity, it does not appear to lead to a reciprocal increase in IRE-binding activity, suggesting that PCBP depletion does not result in the complete disassembly of the FeS cluster in IRP1