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Most importantly, even though differences in the type 1 receptor-binding residues and signaling potency between mature GDF11 and MSTN have been reported 25 , it is difficult to rule out the fact that recombinant GDF11 and MSTN proteins cannot be effectively distinguished due to their high sequence similarity, revealing the possibility that the responses mediated by recombinant GDF11 protein treatment actually reflect the endogenous functions of MSTN

In a press release, Moderna CEO Stphane Bancel touted the strength and versatility of the companys mRNA platform, adding that the approval also marks the first time an mRNA vaccine has been approved for a disease other than COVID-19

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