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233,234 Increased intracellular calcium concentration has been observed in a variety of senescent cells

Proc Natl Acad Sci USA 111 , E52055213 (2014)

Critically, these shared targets are embedded in complex epigenetic networks and feedback loops

Under ocular conditions such as those of DR, a reduction in GPX4 levels can result in increased oxidative stress, consequently impacting the functionality and viability of PR cells (49)