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Its demonstrated efficacy in improving insulin sensitivity via reducing FINS by 31.8% and improving ISI by 66.3% in clinical trials, ameliorating dyslipidemia, reducing HA via decreasing testosterone and LH levels while increasing FSH, attenuating chronic inflammation and oxidative stress, restoring ovarian folliculogenesis and ovulation via normalizing estrous cycles and increasing high-quality oocyte rates, and modulating gut microbiota dysbiosis

The role of neuroinflammation in neurodegenerative diseases: Current understanding and future therapeutic targets

Available studies suggest that PGRMC1 promotes autophagy by directly binding to LC3, a key component of the autophagy machinery, and participates in lipophagy by increasing tubulin tyrosination and interaction with mitochondria

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FIGURE 6 In addition, phytochemicals can also target and modulate various signalling pathways, which also play a role in the development and propagation of seizures