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Low plasma PLP in inflammatory conditions parallels reduction in liver but not muscle PLP, and may reflect tissue-specific mobilization of this cofactor to the sites of inflammation, a hypothesis that has been supported by experimental studies in rats (35, 237)

The liberation of Nrf2 from Keap1 allows Nrf2 accumulation and translocation to the nucleus (Cuadrado et al., 2019

NAC is the nutritional supplement normally consumed to help increase glutathione levels

Massive transcriptome sequencing was performed using the HiSeq 2,500 technique, where 10 million reads per gene were considered for mapping

We integrated the proteomics and ELISA datasets to assess whether the PCC group could be distinguished from the convalescent group using PCA (Fig