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490 Furthermore, we can evaluate the impact of different drug combinations on the p53 signaling pathway via machine learning models, such as stochastic gradient boosting (SGB) or deep learning, to optimize combination therapies

somnifera has been reported to have anticonvulsant, antidepressant, anxiolytic, and anti-Parkinson actions, mostly due to the presence of sitoindosides VIIX, withanolides, and withaferin-A [167]