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Penetration Variability: While more lipophilic than GHK, Pal-GHKs delivery still depends on formulation quality (e.g., emulsions, liposomes), with inconsistent results in poorly designed products

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No change in extracellular GSH levels were observed after 12 hours of CSE exposure, but by 24 and 48 hours there was significantly more extracellular GSH with CSE exposure versus the control (Figure 1A)