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The thiol group is important this sulfur compound allows glutathione to donate electrons to neutralize reactive oxygen species ( ROS ) in the cell

Chan K, Lu R, Chang JC, Kan YW

Classically activated macrophages, defined experimentally by stimulation with lipopolysaccharide (LPS) with or without interferon-gamma (IFN-) but can also include other microbial products, are inflammatory in nature and required to counteract pathogenic microorganisms 15