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Shin J: Clinical pharmacogenomics of warfarin and clopidogrel

Selenium and vitamin E also play supportive roles in glutathione function

A preclinical study suggested its selective anticancer potential by depleting ROS below the levels required for telomerase activation, disrupting redox homeostasis, and suppressing cancer cell proliferation

We cannot make inferences about the direction or mechanisms underlying the relationship between GSH and quality of performance, but we may hypothesize that an increase in GSH could potentially relate to a reduction of oxidative stress produced by a higher neuronal/physiological metabolism that is required for successful cognitive performance

-These conditions generally required several months or longer of sustained pharmacological therapy beyond initial treatment