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The location of the ascorbate-binding site overlaps with the GSH-binding site, suggesting a ping-pong kinetic mechanism for electron transfer at the common Cys20 active site

To address these challenges, future research should integrate multi-omics approaches to delineate the distinct functions of individual PRLM subtypes, develop precision delivery strategies targeting receptorligand interactions, and evaluate their efficacy and safety in early phase clinical trials

The generally protective, antioxidative effects of GSH are reflected in the observations that decreased levels of GSH lead to clinical symptoms in humans and decreased resistance to viruses and other diseases

Statements Author contributions MH: Conceptualization, Investigation, Writing original draft, Writing review & editing, Formal analysis, Resources, Visualization

Joint Support : Collagen serves as the primary component of cartilage, essential for joint flexibility and resilience