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This work is based upon experiments performed at the KWS-2 and MARIA instruments operated by JCNS at the Heinz Maier-Leibnitz Zentrum (MLZ), Garching, Germany

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is supported by the Canadian Institutes of Health Research (201709FDN-CEBA-116200 to G.R.S.), Diabetes Canada (DI-5-17-5302-GS), a Tier 1 Canada Research Chair and a J