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Studies demonstrate that systemic IGF-1 administration results in approximately 60% increases in tissue strength during healing of collagenous extracellular matrices

This selectivity has been characterized in animal studies only

What can be said is that they sit on very different evidence tiers: tesamorelin is FDA-approved with multiple Phase 3 randomized trials for reducing visceral fat in HIV-associated lipodystrophy, while CJC-1295 is unapproved, with only two small early-phase human studies measuring GH and IGF-1 surrogates

CJC-1295 is a GHRH analogue it binds the growth-hormone-releasing-hormone receptor on those same somatotrophs, mimicking the action of endogenous GHRH

When you combine near-100% bioavailability with measurable improvements in endurance, faster muscle recovery, and bulletproof immune function, you get results that simply aren't possible with oral supplements or wishful thinking