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This effect is thought to be related to the high protein content of Spirulina (104)

FIGURE 8 The GSH and hGSH content in BSO-treated sym40-1 roots with nodules was reduced by 94 and 99%, respectively, compared with untreated sym40-1 roots with nodules (Supplementary Table 4)

One plausible explanation for these outcomes is that these drugs might affect lipid metabolism, inducing changes in the structure and composition of HDL, ultimately leading to a loss of its functional properties (Marsche, 2015)