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doi: 10.1179/135100007X200245

The PI3K/Akt pathway, which is positively induced by -catenin 118,119 , acts by phosphorylating GSK-3 to negatively regulate PPAR expression 120

Siegmund B, Zeitz M

, 2001) and although not immediately intuitive, it might be that elevated levels of homocysteine may play some aggravating role in the pathogenesis of schizophrenia through an indirect effect on COMT (Applebaum et al