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Intracellular ROS levels were quantified via fluorescent probe detection (Fig

10.1007/s10554-024-03146-3 115

59 In recent years, it has been demonstrated that iron has become an independent factor affecting bone metabolic disorders, particularly in the context of iron overload in osteoporosis

Additionally, as noted above we also found the up-regulation of Hsp70, a specific chaperone that forms complexes with other co-chaperones in maintaining hemostasis and is associated with intracellular organization of signaling systems and platelet function 24 , and expression of Hsp70 is an endogenous mechanism by which living cells adapt to stress 25