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Intravesical alkalinized lidocaine (PSD597) offers sustained relief from symptoms of interstitial cystitis and painful bladder syndrome

In addition, iodine supplementation in iodine-deficient areas has been associated with an increased risk of thyrotoxicosis, supporting the U-shaped relationship between iodine status and thyroid disorders [17, 18]

However, its efficacy is often limited by incomplete symptom relief and side effects, especially in older populations 5,6,7,8,9

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That internal friction can show up as collagen breakdown, reduced elasticity, uneven tone, and the kind of dullness that makes rest look like it never happened