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A.Al DawishM

doi: 10.1128/IAI.00217-16 222 KannanGCrawfordJAYangCGressittKLIhenatuCKrasnovaINet al

It is composed of two classes of macromolecules, the fibrous proteins and the proteoglycans consisting of core proteins with one or more glycosaminoglycans (GAGs) covalently attached ( Collagens are the main constituents of the ECM comprising around 30% of the whole protein mass in the body ( Collagen is composed of three left-handed polypeptide chains called -chains held together by inter-chain hydrogen bonds