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Recent example showing the crucial role of protein interactions and the differential role of ECM protein isoforms in the assembly of the ECM meshwork

Histol Histopathol 1996;11, 10751088

A more accurate description at this time would be to view it as an immunologically active interface dominated by protein adsorption and opsonization, rather than as a fully defined classical protein corona structure ( From a functional perspective, the protein adsorption interface significantly alters the immunological properties of MSU crystals

CD18 can interact with endothelial cell surface molecules (including binding to ICAM-1) (50, 51), and the homing of neutrophils to the bone marrow is mediated by CXCR4 (52)

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