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[ 248 ] Additionally, many other factors such as Oncogenic HOXB8, [ 46 ] variable shear factor QKI, [ 249 ] miR1423p, [ 250 ] lncRNA AC016727.1, [ 55 ] and lncRNA TRGAS1/miR4500 axis [ 74 ] are capable of targeting BACH1, controlling EMT, and participating in the development of colorectal cancer, esophageal cancer, breast cancer, nonsmall cell lung cancer, and liver cancer individually

doi: 10.1093/infdis/jiz334 5 BeversE

Higher levels of pro-inflammatory cytokines and glial cell markers were observed, and stool samples had higher concentrations of inflammatory mediators such as TNF-, IL-1, IL-6, and IFN- in PD patients colon biopsy tissues, which indicate gastrointestinal inflammation (84) (Figure 2)