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Therefore, further validation using human samples or alternative hyperuricemia models is necessary to establish the robustness of the findings

When sleep-deprived, people are more likely to catch colds, experience slower recovery from illnesses and injuries, and respond less effectively to vaccines

Liu K, Wang C, Ma J, Shi G, Yao X, Fang H, et al

Archived from the original on February 3, 2010

Moreover, studies using animal models where gut permeability is altered because of the direct or indirect genetic or pharmacological manipulations have demonstrated diverse effects on mucosal immune homeostasis and inflammation, including immune adaptation and resistance to colitis