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The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity

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Samples were flash-frozen before later analysis

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Also known as BPC-157 body protection compound-157 , this 15-amino-acid peptide comes from a protein found in human gastric juice

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As expected, incubation with only reduced MESNA (75 mM) yielded no active RNase A (Figure 5)

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