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This pattern mirrors the substantial heterogeneity (I 2 58.7%) seen in a dedicated meta-analysis of Ginkgo biloba for AMS prophylaxis, which reported a non-significant relative risk reduction overall

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Critically ill patients and patients receiving chemotherapy/radiotherapy show severely compromised intestinal barrier integrity

There was no significant difference in the incidence of adverse events and serious adverse events in patients with diabetic neuropathy who took 600 mg/day of lipoic acid for four years compared to those in the placebo group (78)