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This will ultimately provide a rational basis for clinical practice

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Given the interaction between epitalon, DNA and histone proteins, we speculate that the tetrapeptide may trap proteins on the DNA and induce ALT activity

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Previously, we have described the mechanism underlying the development tubular injury of DKD, here we reviewed the protective effect of hypoglycaemic drugs on renal tubules ( Table 1 ), and some new therapeutic strategies, such as stem cell therapies