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Description

Arsenic binding induces a conformational change in the structure of the protein (PML-RARa), facilitating its oligomerization

In the second part of the review, the current evidence of the role of impaired barrier function in the pathophysiology of selected gastrointestinal and liver diseases is discussed

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To quantify cell loss, slides were blinded and a pathologist (K.J.E.) assessed the approximate total acellular tissue area (including abnormalities such as stroma, fat, and necrosis) in 1030 highpower fields for each sample