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Allergic reactions (e.g., ocular swelling, eyelid edema, and conjunctival hyperemia), corneal edema, iritis, ocular inflammation, ocular irritation, superficial keratitis, and superficial ocular infection have been reported in 1% to 10% of patients

[9] Its also prudent to be cautious or avoid NAD+ injections if you have a serious uncontrolled medical condition (for example, end-stage liver or kidney disease or severe heart disease), unless your physician specifically determines its safe

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Its important to understand that viscosupplementation isnt an immediate pain reliever like cortisone injections