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Furthermore, one study suggests that neuronal stimulation, at least in the hippocampus, triggers neuronal glycolysis and the release of lactate from neurons (Zuend et al., 2020) or stimulation with cannabinoids (Jimenez-Blasco et al., 2020)

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Elesclomol-induced increase of mitochondrial reactive oxygen species impairs glioblastoma stem-like cell survival and tumor growth