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Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice

The cultured SGNs were exposed to 100 M peroxynitrite for 48 h (Figure 2C) and immunostaining illustrated that the fluorescence intensity of GPX1 in the peroxynitrite group was significantly reduced compared with that of the control group (Figure 2D)

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A large meal can trigger the body to release more insulin, resulting in low blood sugar levels and a fatigue-inducing slump

The metabolic kynurenic pathways is likely also implicated in ME/CFS, owing to common mutations in IDO2 (76) such as R248W and Y359STOP (77)