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The off-cycle is intended to keep the GH receptor responsive

[,] Effective alternative or additional therapy options must be investigated due to these conditions

"insulin pump day 1" by Erin Stevenson OConnor is licensed under CC BY-SA 2.0

Mutations that decrease the amount of functional MRP2 have also been associated with greater incidence of toxic liver injury and hepatotoxicity during administration of cytotoxic drugs 6,7,8,9