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10 If response or remission is achieved, the same therapy should be continued as maintenance, though rectal preparations may not be preferred by patients for long-term treatment, and oral 5-ASA preparations can be utilized alone (Fig

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Poly(rC)-binding protein 1, acts as a cytosolic iron chaperone in mammalian cells, binding Fe and delivering it to ferritin, thereby limiting cytoplasmic iron toxicity, preventing ferroptosis and lipid peroxidation [31]

More lines of evidence concerning the relationship between H2O2 and Ca2+ signals were provided by the study of H2O2 homeostasis in Arabidopsis (Yang and Poovaiah, 2002)