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J Cereb Blood Flow Metab 37:21122124

Nature 507 (7493), 448454

*Correspondence: Kate Worster, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Apparent kinetic rate ( k app ) reflects the rate of observed VitC signal change caused by both T 1 relaxation and VitC production from DHA, while k reflects only the VitC production rate