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Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

Specimens were immediately spread on culture dishes for cell staining, or treated with ferroptosis inducers, or stored at 80 C until further experiments (RNA extraction and protein isolation)

Research in animals shows that the CLOCK gene rhythm in mast cells is important for baseline histamine release as well as allergic reactions.[ref] The PER2 gene also impacts allergic reactions and mast cell activation.[ref] See your CLOCK, PER, and melatonin genes in the genotype report below

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