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The finding of mitochondrial derived DAMPs (mito-DAMPs) including ROS, NAD + and mitochondrial Ca 2+ release lead to the hypothesis that mitochondrial dysfunction is a contributor to inflammasome activation (Guo et al., 2015

Glutathione Peroxidase: As the name implies, this form of glutathione helps with the breakdown of hydrogen peroxide, which prevents cellular damage

To the other portion, add 2.0 mL of standard sodium chloride solution (prepared by dissolving 0.126 g of sodium chloride, dried at 105C for 2 hours, in water in a 1000 mL volumetric flask and diluting to volume to obtain a solution containing 50 g of sodium per 1 mL), dilute with water to volume, mix well, and use as the reference solution

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The lysosome contains enzymes and peroxides that are able to digest the pathogen