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Glutathione supplementation effectively diminished glucose-induced neutrophil elastase and cytosolic ROS production and suppressed NETs formation in high glucose environment [15]

This protocol was chosen due to its demonstrated capacity to generate iHLOs with high CYP enzyme activity, particularly CYP3A4, which is crucial for our subsequent compound or drug metabolism and toxicology evaluations

Rhein improves renal fibrosis by restoring cpt1a-mediated fatty acid oxidation through sirT1/STAT3/twist1 pathway

Altered endocrine, cytokine signaling and oxidative stress: a plausible reason for differential changes in testicular cells in diet-induced and genetically-inherited obesity in adult rats