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Critical role of Astrocyte NAD(+) Glycohydrolase in myelin injury and regeneration

According to the Mayo Clinic, most people consume adequate amounts of B vitamins through their diet, though the elderly, particularly those with pernicious anemia, athletes, strict vegetarians, and people who consume a lot of alcohol may be deficient in the B vitamins and may require injections or oral supplementation of B vitamins or vitamin B-12, in particular

Cell Metabolism 24(6):795-806. [doi.org]

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Those with Poor Diets: Individuals who dont consume a balanced diet may be at risk of vitamin B12 deficiency