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In summary, plant-derived bioactive compoundsespecially those targeting autophagyhave shown promising clinical results against MAFLD and represent valuable candidates for future drug development

Clinical studies and meta-analyses suggest that ALA supplementation can lead to small but meaningful improvements in fasting glucose and insulin sensitivity, particularly in people with type 2 diabetes or metabolic syndrome.2 24 That said, these effects are generally modest and ALA should never be viewed as a substitute for prescribed diabetes medications

Granfors, M

To minimize these limitations, we performed a random effects model, a Leave-One-Out sensitivity analysis

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