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Proper medical supervision is essential

doi:10.1016/j.eprac.2023.09.012 Morgentaler A, Dhindsa S, Dobs AS, et al

step (b) provides a set of mutagenic oligonucleotides that encode all nineteen naturally-occurring amino acid variants for each targeted codon, thereby generating all 19 possible natural amino acid changes at each amino acid codon mutagenized