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While causality remains debated, GLP-1 receptor agonists associate with increased pancreatitis risk in some populations

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[200] Moreover, a prospective cohort study aimed to determine the association between an index of radiographically assessed oral health, Panoramic Tomographic Index (PTI), and cardiovascular and all-cause mortality, major adverse cardiovascular events (MACEs) and episodes of bacteremia and laboratory measurements during a three-year prospective follow-up in chronic kidney disease (CKD) stage 4-5 patients not on maintenance dialysis at baseline

Free Radic Res 51:460469

The majority of patients also tolerate the therapy very well, particularly if in the hands of professional practitioners