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In recent years, attention has turned to two promising compounds, urolithin A (UroA) and spermidine, which have been shown to enhance these pathways and offer potential benefits for human health

Vorasidenib is the first systemic treatment approved specifically for this patient population, marking a milestone after more than 20 years without new therapeutic options for low-grade gliomas [28]

Hills RD et al

Rarer causes include arterial dissection and vasculitis, as well as inflammation of the blood vessel walls (Schramm et al., 2011)

Recent studies have also emphasized the role of host-directed therapies and novel drug delivery systems to enhance treatment efficacy