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Zinc deficiency promotes the production of IL-1 by increasing the accessibility of the IL-1 promoter, which possibly results in a constitutive IL-1 production even in the absence of danger signals

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The GluN subunits contain an extracellular amino-terminal domain (ATD), a ligand-binding domain (LBD), a transmembrane domain (TMD), and an intracellular C-terminal domain (CTD)

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