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Key molecular signaling pathways in the AKI-CKD transition The AKI-CKD transition represents a multifaceted pathological phenomenon driven by persistent renal inflammation, tubular dysfunction, and excessive ECM deposition, which ultimately leads to irreversible renal fibrosis and ESRD

The individual component scores were derived and compared pairwise with the first and second set of scores

doi: 10.1016/j.ecoenv.2004.06.010 50 ParkS.-I.KimY.-S.KimJ.-J.MokJ.-E.KimY.-H.ParkH.-M.et al

Kornblau SM, Andreeff M , Qui YH, Patel S, Thomas D, Giles F, Beran M, Estrov Z

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