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Description

Preclinical studies indicated that it targeted the bacterial flavoenzyme TrxR, essential for M.tb survival by protecting against oxidative and nitrosative stress

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The active form of MAPKKK phosphorylates MEK1/2 (MAPKK), which in turn phosphorylates ERK1/2 (MAPK), favoring its nuclear translocation and activation of target transcription factors (90)

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Psychiatry 16, 12341246

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Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese

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Notably, different regulated cell death pathways are functionally complementary rather than mutually exclusive during periodontitis progression

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