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For instance, TNF has been shown to induce the release of mitochondrial DNA (mtDNA), which then activates cGAS-STING-mediated IFN responses, contributing to the progression of arthritis

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There was an increased incidence of Harderian gland adenomas in males and females in all treatment groups (starting at doses equivalent to 0.002 times the human 5 mg intravenous dose, based on body surface area, mg/m2)

In vitro release studies demonstrated that the liposomal drug depot displayed a slower release than free DSP at pH 5.5 (Fig