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Nuclear IGF-1R in cancers is positively correlated with tumor stage and presents higher protein levels in metastatic cancer (Codony-Servat et al., high /IGF-1R high murine alveolar rhabdomyosarcoma cells and were associated with greater anchorage-independent colony formation ability (Aslam et al., Niche and IGF-1R-Mediated Stemness Expressions in Stem Cells and Cancers The fact that IGF-1R signaling promotes and maintains stemness in both stem cells and CSCs or cancer reprogramming raises the following questions: What transforms IGF-1R signaling from a traditional pathway to being central to the regulation of stem cell properties

Analysis of the expression of metabolism-related genes and histopathology of the hepatopancreas of white shrimp Litopenaeus vannamei fed with aflatoxin B1

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IB binds to the p65 subunit and is present in the cytoplasm, inhibiting the transcription factor activity of NF-B

Sci World J 2014:231635231635 Garcia J, Costa VM, Carvalho A, Baptista P, de Pinho PG, de Lourdes BM, Carvalho F (2015) Amanita phalloides poisoning: mechanisms of toxicity and treatment