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doi:10.1016/s1054-3589(08)60594-3 Return to citation in text: [1] Corti, A

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Overall, these trends underscore the increasing recognition of DTP cells as a clinically relevant, non-genetic precursor to therapeutic resistance, contributing to minimal residual disease and enabling the emergence of stable resistant populations, as demonstrated in EGFR-mutant models and other systems ( 3.2 Experimental models and functional definition of drug-tolerant persister cells Across 175 experimental and experimentalclinical studies, several convergent methodological principles emerged despite substantial variations in cancer types, therapeutic agents, exposure conditions, and detection platforms

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