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The maximum drug concentration in plasma ( C max ), the time to reach maximum drug concentration ( T max ) and area under the plasma concentrationtime curve ( AUC (0-t) ) of water extraction were 6.37 3.61 ng / mL, 0.25 0.13 h and 5.14 1.85 ng / mL*h, respectively

The reason may be that the high-lipid diet induced oxidative stress (Raghuvaran et al., 2023) and inflammation (Dai et al., 2022), which in turn affected the intestinal development

Notably, children of fathers with metabolic syndrome exhibit significantly elevated risks of metabolic syndrome regardless of sex [212]

Previous studies have suggested that IF may induce mild mitochondrial stress, leading to improved mitochondrial function and reduced ROS generation over time 37

Finally, it is important to be aware that NAPstars monitor the soluble pool of NADPH and NADP + , they do not see protein-bound NADP, which may constitute a significant fraction of total NADP in some situations [32]