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These volumetric deficits correlate with functional impairments: positron emission tomography (PET) scans reveal hypometabolism in the dorsolateral PFC and hyperactivation of the amygdala during negative emotional stimuli, mirroring neural signatures observed in non-alcoholic MDD patients (Amico et al

Cox17 protein is an auxiliary factor involved in the control of the mitochondrial contact site and cristae organizing system

This network serves as a pivotal hub for inflammation and bone metabolic imbalance, making innate immunity a novel therapeutic target for OP treatment ( Mechanisms of innate immune cells in osteoporosis Innate immune cells constitute a vital component of the bone microenvironment, regulating the differentiation, function, and survival of osteoblasts and osteoclasts through direct contact or secretion of effector molecules (Xu J